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Clobetasol propionate
Clobetasol propionate 〔(Clobetasol Propionate Topical Ointment 0.05% Information - Drug Encyclopedia )〕 is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, vitiligo, lichen sclerosus, and lichen planus.〔(CLOBETASOL PROPIONATE CREAM USP, 0.05% CLOBETASOL PROPIONATE OINTMENT USP, 0.05% )〕
Clobetasol propionate is marketed and sold worldwide under numerous names including Clobex, Clob-x (Colombia), Clovate, Clonovate (T.O. Chemicals, Thailand), Cormax (Watson, US), Pentasol (Colombia), Cosvate (India), Temovate (US), Dermovate (GlaxoSmithKline, Pakistan, Portugal, Israel), Olux, Tenovate, Dermatovate, Butavate, Movate, Novate, and Powercort.〔(• Ulotka Novate / Clobetasoli propionas - leki i suplementy diety, dawkowanie, skład, zastosowanie, opis - DOZ.pl )〕
==Uses==
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,〔Hull C, McKeough M, Sebastian K, Kriesel J, Spruance S. Valacyclovir and topical clobetasol gel for the episodic treatment of herpes labialis: a patient-initiated, double- blind, placebo-controlled pilot trial. J Eur Acad Derma- tol Venereol. 2009;23(3):263-267〕 psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, vitiligo, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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